A case of primary immune deficiency presenting with nephrotic syndrome


Aydin Z., Gursu M., Ozturk S., KILIÇASLAN I., KAZANCIOĞLU R.

CLINICAL KIDNEY JOURNAL, cilt.3, sa.5, ss.456-458, 2010 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 3 Sayı: 5
  • Basım Tarihi: 2010
  • Doi Numarası: 10.1093/ndtplus/sfq083
  • Dergi Adı: CLINICAL KIDNEY JOURNAL
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, CAB Abstracts, EMBASE, Veterinary Science Database, Directory of Open Access Journals
  • Sayfa Sayıları: ss.456-458
  • Anahtar Kelimeler: amyloidosis, common variable immunodeficiency, nephrotic syndrome
  • İstanbul Üniversitesi Adresli: Evet

Özet

Common variable immunodeficiency (CVID) is the most common form of severe antibody deficiency. The disorder is associated with a broad spectrum of clinical manifestations, including infections and chronic lung, gastrointestinal and autoimmune diseases. A 29-year-old female patient has had frequent sinopulmonary infections and gastroenteritis for the last 20 years and had been given broad-spectrum antibiotics for treatment. Immunoglobulin (Ig) levels were at undetectable levels. Renal biopsy was consistent with AA amyloidosis. She is now under follow-up with periodic intravenous Ig treatment without any infection during the last 10 months. CVID must be kept in mind in patients with recurrent sinopulmonary infections.