The role of unfolded protein response in the pathogenesis of endometriosis: contribution of peritoneal fluid.

Ekiz-Yilmaz T., Isildar B., Gezer A., Kankaya D., Cansiz-Ersoz C., Kayisli U. A., ...Daha Fazla

Reproductive biomedicine online, cilt.42, ss.1-15, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 42
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1016/j.rbmo.2020.09.012
  • Dergi Adı: Reproductive biomedicine online
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.1-15
  • Anahtar Kelimeler: Endometriosis, Endoplasmic reticulum stress, Human endometrial stromal cells, Peritoneal fluid, p-IRE1, ENDOPLASMIC-RETICULUM STRESS, MESENCHYMAL TRANSITION, EUTOPIC ENDOMETRIUM, STROMAL CELLS, APOPTOSIS, EXPRESSION, CYTOKINES, PROLIFERATION, BIOMARKERS, WOMEN
  • İstanbul Üniversitesi Adresli: Evet

Özet

Research question: Endoplasmic reticulum stress (ERS) is caused by the accumulation of the misfolded or unfolded proteins in the endoplasmic reticulum and induces the unfolded protein response (UPR). Peritoneal fluid is important in the pathogenesis of endometriosis. In this study, the role of UPR associated with ERS in endometriosis, and peritoneal fluid, were investigated.