A CBCT Study for Anatomic Variations of Osteomeatal complex in Patients With Cleft Lip and Palate

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Göksel S., Özcan İ.

Cleft Palate-Craniofacial Journal, vol.0, no.0, pp.1-8, 2021 (SCI-Expanded)

  • Publication Type: Article / Article
  • Volume: 0 Issue: 0
  • Publication Date: 2021
  • Doi Number: 10.1177/10556656211053773
  • Journal Name: Cleft Palate-Craniofacial Journal
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CAB Abstracts, CINAHL, Educational research abstracts (ERA), EMBASE, Linguistics & Language Behavior Abstracts, MEDLINE, Veterinary Science Database
  • Page Numbers: pp.1-8
  • Istanbul University Affiliated: Yes


Objective: To evaluate the anatomy and variations of osteomeatal complex (OMC) by comparing patients with nonsyndromic cleft lip and palate (CLP) and control group. Design: This case-control study was retrospectively analyzed using cone-beam computed tomography data. Setting: Istanbul University Faculty of Dentistry Department of Dentomaxillofacial Radiology. Patients: The study was conducted with 100 patients (44 females, 56 males) with CLP and 100 patients in the control group, which matched gender and age (with a maximum difference of 3 years). Variables: OMC variations are grouped as follows: ethmoidal, conchal, uncinate process, and septal variations. Then, we evaluated the presence of these OMC variations and compared them between the two groups. Statistical analysis: The McNemar’s test was used to determine any significant differences between the groups for all indices at the 95% confidence level. Results: The most common anatomic variation in this study was Agger nasi cell (97%) and concha bullosa (97%) in the patients with CLP, while Agger nasi cell was the most common variation (99%) in the controls. Moreover, the atelectatic uncinate process was the least observed variation in both groups (1%). The incidences of paradoxical concha (58%;42%), bifid concha (29%;11%), deviated nasal septum (92%;80%) were significantly higher in the CLP group (p < 0.05). Conclusions: The statistically significant results found when comparing OMC anatomy between the two groups reveal the importance of three-dimensional evaluation before functional endoscopic sinus surgery in patients with CLP.