Quantitative detection of methylated SOCS-1 in schizophrenia and bipolar disorder considering SOCS-1-1478CA/del polymorphism and clinical parameters

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Aytac H. M., Pehlivan S., Pehlivan M., Oyaci Y.

IRISH JOURNAL OF MEDICAL SCIENCE, vol.192, no.2, pp.775-783, 2023 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 192 Issue: 2
• Publication Date: 2023
• Doi Number: 10.1007/s11845-022-03030-w
• Journal Name: IRISH JOURNAL OF MEDICAL SCIENCE
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED)
• Page Numbers: pp.775-783
• Keywords: Bipolar disorder, DNA methylation, PCR-RFLP, qMS-PCR, Schizophrenia, SOCS-1, TOXOPLASMA-GONDII, JAK/STAT PATHWAY, RATING-SCALE, SERUM-LEVELS, ASSOCIATION, BLOOD, GENE, INFLAMMATION, RELIABILITY, SUPPRESSOR
• Istanbul University Affiliated: Yes

Abstract

Background We aimed to investigate the quantitative detection of methylated suppressor of cytokine signaling-1 (SOCS-1) in schizophrenia (SCZ) and bipolar disorder (BD), considering SOCS-1 -1478CA/del polymorphism and clinical parameters.