Quantitative detection of methylated SOCS-1 in schizophrenia and bipolar disorder considering SOCS-1-1478CA/del polymorphism and clinical parameters


Aytac H. M. , Pehlivan S. , Pehlivan M., Oyaci Y.

IRISH JOURNAL OF MEDICAL SCIENCE, 2022 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Publication Date: 2022
  • Doi Number: 10.1007/s11845-022-03030-w
  • Title of Journal : IRISH JOURNAL OF MEDICAL SCIENCE
  • Keywords: Bipolar disorder, DNA methylation, PCR-RFLP, qMS-PCR, Schizophrenia, SOCS-1, TOXOPLASMA-GONDII, JAK/STAT PATHWAY, RATING-SCALE, SERUM-LEVELS, ASSOCIATION, BLOOD, GENE, INFLAMMATION, RELIABILITY, SUPPRESSOR

Abstract

Background We aimed to investigate the quantitative detection of methylated suppressor of cytokine signaling-1 (SOCS-1) in schizophrenia (SCZ) and bipolar disorder (BD), considering SOCS-1 -1478CA/del polymorphism and clinical parameters.