Tumor necrosis factor gene polymorphisms in Turkish patients with sarcoidosis

SEYHAN E. C., CETINKAYA E., ALTIN S., GUNLUOGLU Z., Demir A., KOKSAL V., ...Daha Fazla

INTERNAL MEDICINE, cilt.47, sa.9, ss.833-838, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 47 Sayı: 9
  • Basım Tarihi: 2008
  • Doi Numarası: 10.2169/internalmedicine.47.0703
  • Dergi Adı: INTERNAL MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.833-838
  • İstanbul Üniversitesi Adresli: Evet

Özet

Background As reported recently, some gene polymorphisms are suspected to determine susceptibility to sarcoidosis and are held responsible for the extent and progression of the disease. Polymorphism at -857 locus of tumor necrosis factor (TNF)-alpha gene is considered to be a predisposition factor in sarcoidosis and held responsible for pathogenesis of the disease. We compared these polymorphisms in healthy Turkish control subjects and Turkish patients with sarcoidosis.