Tumor necrosis factor gene polymorphisms in Turkish patients with sarcoidosis

SEYHAN, Ekrem; CETINKAYA, Erdogan; ALTIN, Sedat; GUNLUOGLU, Zeki; Demir, ADALET; KOKSAL, Vedat; Issever, HALİM

doi:10.2169/internalmedicine.47.0703

Tumor necrosis factor gene polymorphisms in Turkish patients with sarcoidosis

SEYHAN E. C., CETINKAYA E., ALTIN S., GUNLUOGLU Z., Demir A., KOKSAL V., ...Daha Fazla

INTERNAL MEDICINE, cilt.47, sa.9, ss.833-838, 2008 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 47 Sayı: 9
Basım Tarihi: 2008
Doi Numarası: 10.2169/internalmedicine.47.0703
Dergi Adı: INTERNAL MEDICINE
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.833-838
İstanbul Üniversitesi Adresli: Evet

Özet

Background As reported recently, some gene polymorphisms are suspected to determine susceptibility to sarcoidosis and are held responsible for the extent and progression of the disease. Polymorphism at -857 locus of tumor necrosis factor (TNF)-alpha gene is considered to be a predisposition factor in sarcoidosis and held responsible for pathogenesis of the disease. We compared these polymorphisms in healthy Turkish control subjects and Turkish patients with sarcoidosis.