Tumor necrosis factor gene polymorphisms in Turkish patients with sarcoidosis
INTERNAL MEDICINE, vol.47, no.9, pp.833-838, 2008 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 47 Issue: 9
- Publication Date: 2008
- Doi Number: 10.2169/internalmedicine.47.0703
- Journal Name: INTERNAL MEDICINE
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.833-838
- Istanbul University Affiliated: Yes
Abstract
Background As reported recently, some gene polymorphisms are suspected to determine susceptibility to sarcoidosis and are held responsible for the extent and progression of the disease. Polymorphism at -857 locus of tumor necrosis factor (TNF)-alpha gene is considered to be a predisposition factor in sarcoidosis and held responsible for pathogenesis of the disease. We compared these polymorphisms in healthy Turkish control subjects and Turkish patients with sarcoidosis.