Effects of upper limb ischemia-reperfusion on regional oxidative stress during aortic surgery with moderate hypothermia

Balci E., Demir Z. A., Ozay H. Y., Vardar K., Karduz G., Aksu U., ...More

JOURNAL OF CARDIAC SURGERY, vol.36, no.4, pp.1361-1369, 2021 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 36 Issue: 4
  • Publication Date: 2021
  • Doi Number: 10.1111/jocs.15409
  • Journal Name: JOURNAL OF CARDIAC SURGERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CINAHL, EMBASE, MEDLINE
  • Page Numbers: pp.1361-1369
  • Keywords: central venous and arterial CO2 pressure gap, central venous oxygen saturation, ischemi-reperfusion injury, lactate, NIRS
  • Istanbul University Affiliated: Yes

Abstract

Introduction This study aims to evaluate the effect of acute, iatrogenic right arm ischemia and reperfusion (I/R) due to right axillary cannulation on regional oxidative stress using tissue perfusion markers such as central venous oxygen saturation, lactate, the difference between central venous and arterial CO2 pressure, near-infrared spectroscopy (NIRS) measurements, and biomarkers like sialic acid, malondialdehyde, advanced oxidative protein products in aortic surgery with moderate hypothermia.