The relation between serum MDA and cystatin C levels in chronic spinal cord injury patients

Kocak H., Oner-Iyidogan Y. , Gurdol F., Kocak T. , Esin D.

CLINICAL BIOCHEMISTRY, vol.38, no.11, pp.1034-1037, 2005 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 38 Issue: 11
  • Publication Date: 2005
  • Doi Number: 10.1016/j.clinbiochem.2005.08.005
  • Journal Name: CLINICAL BIOCHEMISTRY
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.1034-1037

Abstract

Objectives: The assessment of renal function is particularly important in patients with spinal cord injury (SCI). Creatinine (Cr) is known to be unsuitable as a marker of renal function in SCI because of muscle wasting. Although cystatin C (cys-C) is more reliable than Cr, its expression may be affected by oxidative stress accompanying SCI. The aim of the study was to estimate the cys-C levels in SCI patients with normal functioning kidneys. The prooxidant/antioxidant state in plasma of the patients and controls was measured, and any correlations between these parameters and cys-C were determined.