TTF-l EXPRESSION IN SMALL CELL NEUROENDOCRINE CARCINOMAS OF THE LARYNX
TURKISH JOURNAL OF PATHOLOGY, vol.21, pp.17-20, 2005 (ESCI, Scopus, TRDizin)
- Publication Type: Article / Article
- Volume: 21
- Publication Date: 2005
- Journal Name: TURKISH JOURNAL OF PATHOLOGY
- Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, EMBASE, MEDLINE, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
- Page Numbers: pp.17-20
- Istanbul University Affiliated: Yes
Abstract
Small cell neuroendocrine carcinomas of the larynx are uncommon neoplasms-Differential diagnosis includes a limited variety of tumors such as typical carcinoid and atypical carcinoid tumors of the larynx and metastatic small cell lung carcinomas-In this study, 4 cases ol laryngeal small cell carcinoma ol neuroendocrine type were studied for morphological and immunohistochemical features. Three primary laryngeal small cell carcinomas-as well as one metastatic small cell lung carcinoma were detected to be immunopositive for TTF-1. Considering literature data and our findings, the value of TIF-1 expression was found to be questionable in the differential diagnosis between primary and metastatic small cell carcinomas of the larynx.