TTF-l EXPRESSION IN SMALL CELL NEUROENDOCRINE CARCINOMAS OF THE LARYNX

Ozluk Y., GÜLLÜOĞLU M.

TURKISH JOURNAL OF PATHOLOGY, cilt.21, ss.17-20, 2005 (ESCI) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 21
  • Basım Tarihi: 2005
  • Dergi Adı: TURKISH JOURNAL OF PATHOLOGY
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, EMBASE, MEDLINE, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.17-20
  • İstanbul Üniversitesi Adresli: Evet

Özet

Small cell neuroendocrine carcinomas of the larynx are uncommon neoplasms-Differential diagnosis includes a limited variety of tumors such as typical carcinoid and atypical carcinoid tumors of the larynx and metastatic small cell lung carcinomas-In this study, 4 cases ol laryngeal small cell carcinoma ol neuroendocrine type were studied for morphological and immunohistochemical features. Three primary laryngeal small cell carcinomas-as well as one metastatic small cell lung carcinoma were detected to be immunopositive for TTF-1. Considering literature data and our findings, the value of TIF-1 expression was found to be questionable in the differential diagnosis between primary and metastatic small cell carcinomas of the larynx.