Halogenated secondary metabolites from Laurencia obtusa


Aydogmus Z., Imre S., Ersoy L., Wray V.

NATURAL PRODUCT RESEARCH, vol.18, no.1, pp.43-49, 2004 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 18 Issue: 1
  • Publication Date: 2004
  • Doi Number: 10.1080/1057563031000122086
  • Journal Name: NATURAL PRODUCT RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.43-49
  • Keywords: Laurencia obtusa, Rhodomelaceae, red alga, sesquiterpene, acetogenin, ABSOLUTE-CONFIGURATION, NIPPONICA YAMADA, ROGIOLENYNE-A, MARINE PLANTS, IL-ROGIOLO, CONSTITUENTS, ISOPRELAUREFUCIN, ACETOGENINS, MICROCLADIA, COMPOUND
  • Istanbul University Affiliated: Yes

Abstract

A new sesquiterpene (1), and a halogenated C-15 acetogenin (2), a stereoisomer of neoisoprelaurefucin were isolated from Laurencia obtusa. Four known compounds laurencienyne (3), rogiolenyne B (4), obtusenol (5), and (3E)-dactomelyne (6) were also isolated from this alga. Rogiolenyne B (4) and (3E)-dactomelyne (6) were found for the first from this species. The structures of these compounds were elucidated by spectroscopic methods. The unambiguous assignments of the H-1 and C-13 NMR spectral data of (5) and C-13 NMR data of (6) were also reported for the first time.