The positive effect of adenoma weight and oxyphil cell content on preoperative localization with Tc-99m-sestamibi scanning for primary hyperparathyroidism

Erbil, Yesim; Kapran, Yersu; Issever, HALİM; Barbaros, Umut; Adalet, Işık; Dizdaroglu, Ferhunde; Bozbora, Alp; Ozarmagan, Selcuk; TEZELMAN, Serdar

doi:10.1016/j.amjsurg.2007.01.040

The positive effect of adenoma weight and oxyphil cell content on preoperative localization with Tc-99m-sestamibi scanning for primary hyperparathyroidism

Erbil Y., Kapran Y., Issever H., Barbaros U., Adalet I., Dizdaroglu F., ...More

AMERICAN JOURNAL OF SURGERY, vol.195, no.1, pp.34-39, 2008 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 195 Issue: 1
Publication Date: 2008
Doi Number: 10.1016/j.amjsurg.2007.01.040
Journal Name: AMERICAN JOURNAL OF SURGERY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.34-39
Keywords: adenoma weight, oxyphil cell, parathyroid adenoma, sestamibi scan, HIGH-RESOLUTION ULTRASONOGRAPHY, PARATHYROID-HORMONE ASSAY, SESTAMIBI SCAN, 99M SESTAMIBI
Istanbul University Affiliated: Yes

Abstract

Background: Although the sensitivity of sestamibi scanning (MIBI) is high in patients with solitary parathyroid adenomas, negative sestamibi scan results are inevitable. The exact mechanism of visualization of abnormal and hyperfunctioning parathyroid tissue is not yet clear. The aims of this clinical study were (1) to evaluate positive and negative sestamibi scan results with regard to adenoma weight and oxyphil cell content and (2) to compare the effects of adenoma weight and oxyphil cell content on the results of sestamibi scanning.