TURKISH JOURNAL OF MEDICAL SCIENCES, vol.47, no.6, pp.1819-1825, 2017 (SCI-Expanded)
Background/aim: Juvenile idiopathic arthritis (JIA) is a chronic complex autoimmune disease. Genetic and environmental factors increase the risk of JIA. It is accepted that alterations in immune system pathways play an important role in the pathogenesis of JIA. The aim of the study was to investigate the possible association between immune system regulatory gene polymorphisms and JIA in Turkish patients.