INFLAMMATORY MARKERS AND INTERLEUKIN-6 (-174G/C) GENE POLYMORPHISM IN PERIPHERAL VASCULAR DISEASE
NOBEL MEDICUS, cilt.13, sa.1, ss.21-25, 2017 (ESCI, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 13 Sayı: 1
- Basım Tarihi: 2017
- Dergi Adı: NOBEL MEDICUS
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus
- Sayfa Sayıları: ss.21-25
- İstanbul Üniversitesi Adresli: Evet
Özet
Objective: Peripheral vascular disease (PVD) is an atherosclerotic and prothrombotic process leading cause of mortality. Atherosclerosis is recognized as a chronic inflammatory disease and starts as a protective response in damage to the endothelium and smooth muscle cells of the wall of the artery. The aim of this study was to investigate the association of interleukin-6 (-174 G/C) polymorphism with pro- and anti-inflammatory cytokines such as Interleukin-6 (IL-6), Interleukin-8 (IL-8), and Interleukin-1 Receptor antagonist (IL-1Ra) in PVD.