The Association of Glycemic Markers with Plasma Adipocytokine Levels in Women with Gestational Diabetes

Oztop N., Kusku-Kiraz Z., Dervisoglu E., Dinccag N., Genc S.

JOURNAL OF DIABETES & METABOLISM, vol.7, no.9, 2016 (ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 7 Issue: 9
  • Publication Date: 2016
  • Doi Number: 10.4172/2155-6156.1000699
  • Journal Name: JOURNAL OF DIABETES & METABOLISM
  • Journal Indexes: Emerging Sources Citation Index (ESCI)
  • Keywords: Gestational diabetes mellitus, Dipocytokines, 1,5-anhydro-D-glucitol (1,5-AG), Continuous glucose monitoring system, HbA1c, NECROSIS-FACTOR-ALPHA, TNF-ALPHA, INSULIN-RESISTANCE, INTERLEUKIN-6 DOES/DOES, INFLAMMATORY MEDIATORS, GLUCOSE-HOMEOSTASIS, BENEFICIAL ROLE, PREGNANT-WOMEN, BETA-CELLS, HYPERGLYCEMIA
  • Istanbul University Affiliated: Yes

Abstract

Introduction: Alterations in the synthesis of cytokines have been demonstrated in gestational diabetes (GDM), but the association of cytokines with short- and long-term glycemic markers has not been defined clearly. In this study, the variations in the plasma levels of visfatin, TNF-alpha, IL-1 beta, IL-6, and IL-10 were investigated and theirassociations with glycemic markers -HbA1C, fructosamine, 1,5-anhydro-D-glucitol (1,5-AG), and continuous glucose monitoring system (CGMS) parameters were evaluated.