A New Diterpenoid Alkaloid from the Roots of a White-Flowering Aconitum orientale Sample

Mericli A. H., Cagal-Yurdusever N., ÖZÇELİK H., Zapp J., Kiemer A. K.

HELVETICA CHIMICA ACTA, vol.95, no.2, pp.314-319, 2012 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 95 Issue: 2
  • Publication Date: 2012
  • Doi Number: 10.1002/hlca.201100139
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.314-319
  • Istanbul University Affiliated: Yes


From the roots of a white-flowering Aconitum orientale Miller sample, collected in Artvin-Savsat, Turkey, a new diterpenoid alkaloid named aconitorientaline (1) was isolated, along with the known diterpenoid alkaloids septentiriodine, lappaconitine, finaconitine, ranaconitine, puberanidine and delstaphinine (Fig.). The structure of 1 was established on the basis of 1H- and 13C-NMR, DEPT, 1H,1H-COSY, NOESY, HSQC, and HMBC studies. All the known compounds were identified by comparison of their 1H- and 13C-NMR data and co-TLC behavior with those of authentic samples.