Intracranial Angioplasty and Stent Placement After Stenting and Aggressive Medical Management for Preventing Recurrent Stroke in Intracranial Stenosis (SAMMPRIS) Trial: Present State and Future Considerations

Qureshi A. I. , Al-Senani F. M. , Husain S., Janjua N. A. , Lanzino G., Lavados P. M. , ...More

JOURNAL OF NEUROIMAGING, vol.22, no.1, pp.1-13, 2012 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 22 Issue: 1
  • Publication Date: 2012
  • Doi Number: 10.1111/j.1552-6569.2011.00685.x
  • Title of Journal : JOURNAL OF NEUROIMAGING
  • Page Numbers: pp.1-13


OBJECTIVE The results of prematurely terminated stenting and aggressive medical management for preventing recurrent stroke in intracranial stenosis (SAMMPRIS) due to excessively high rate of stroke and death in patients randomized to intracranial stent placement is expected to affect the practice of endovascular therapy for intracranial atherosclerotic disease. The purpose of this report is to review the components of the designs and methods SAMMPRIS trial and to describe the influence of those components on the interpretation of trial results.