Intracranial Angioplasty and Stent Placement After Stenting and Aggressive Medical Management for Preventing Recurrent Stroke in Intracranial Stenosis (SAMMPRIS) Trial: Present State and Future Considerations

Qureshi A. I., Al-Senani F. M., Husain S., Janjua N. A., Lanzino G., Lavados P. M., ...More

JOURNAL OF NEUROIMAGING, vol.22, no.1, pp.1-13, 2012 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 22 Issue: 1
  • Publication Date: 2012
  • Doi Number: 10.1111/j.1552-6569.2011.00685.x
  • Journal Name: JOURNAL OF NEUROIMAGING
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1-13
  • Istanbul University Affiliated: No

Abstract

OBJECTIVE The results of prematurely terminated stenting and aggressive medical management for preventing recurrent stroke in intracranial stenosis (SAMMPRIS) due to excessively high rate of stroke and death in patients randomized to intracranial stent placement is expected to affect the practice of endovascular therapy for intracranial atherosclerotic disease. The purpose of this report is to review the components of the designs and methods SAMMPRIS trial and to describe the influence of those components on the interpretation of trial results.