Mediastinal staging by videomediastinoscopy in clinical N1 non-small cell lung cancer: a prospective multicentre study

Decaluwe H., DOOMS C., D'JOURNO X. B., CALL S., SANCHEZ D., HAAGER B., ...More

EUROPEAN RESPIRATORY JOURNAL, vol.50, no.6, 2017 (SCI-Expanded) identifier identifier identifier


A quarter of patients with clinical N1 (cN1) non-small cell lung cancer (NSCLC) based on positron emission tomography-computed tomography (PET-CT) imaging have occult mediastinal nodal involvement (N2 disease). In a prospective study, endosonography alone had an unsatisfactory sensitivity (38%) in detecting N2 disease. The current prospective multicentre trial investigated the sensitivity of preoperative mediastinal staging by video-assisted mediastinoscopy (VAM) or VAM-lymphadenectomy (VAMLA).