Mediastinal staging by videomediastinoscopy in clinical N1 non-small cell lung cancer: a prospective multicentre study

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Decaluwe H., DOOMS C., D'JOURNO X. B., CALL S., SANCHEZ D., HAAGER B., ...More

EUROPEAN RESPIRATORY JOURNAL, vol.50, no.6, 2017 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 50 Issue: 6
• Publication Date: 2017
• Doi Number: 10.1183/13993003.01493-2017
• Journal Name: EUROPEAN RESPIRATORY JOURNAL
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Istanbul University Affiliated: Yes

Abstract

A quarter of patients with clinical N1 (cN1) non-small cell lung cancer (NSCLC) based on positron emission tomography-computed tomography (PET-CT) imaging have occult mediastinal nodal involvement (N2 disease). In a prospective study, endosonography alone had an unsatisfactory sensitivity (38%) in detecting N2 disease. The current prospective multicentre trial investigated the sensitivity of preoperative mediastinal staging by video-assisted mediastinoscopy (VAM) or VAM-lymphadenectomy (VAMLA).