VEGF-A and FGF gene therapy accelerate healing of ischemic colonic anastomoses (experimental study)

Adas, Gokhan; Percem, Askin; Adas, Mine; Kemik, Ozgur; Arikan, Soykan; Ustek, Duran; Cakiris, ARİS; Abaci, NESLİHAN; Kemik, Ahu; Kamali, Gulcin; Karahan, Servet; Akcakaya, Adem; Karatepe, Oguzhan

doi:10.1016/j.ijsu.2011.05.002

VEGF-A and FGF gene therapy accelerate healing of ischemic colonic anastomoses (experimental study)

Adas G., Percem A., Adas M., Kemik O., Arikan S., Ustek D., ...Daha Fazla

INTERNATIONAL JOURNAL OF SURGERY, cilt.9, sa.6, ss.467-471, 2011 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 9 Sayı: 6
Basım Tarihi: 2011
Doi Numarası: 10.1016/j.ijsu.2011.05.002
Dergi Adı: INTERNATIONAL JOURNAL OF SURGERY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.467-471
İstanbul Üniversitesi Adresli: Evet

Özet

Background: Reducing ischemic damage is one of the goals of surgery. The aim of this study was to apply human VEGF-A and FGF-2 DNA-mediated gene therapy in order to identify their effects in the healing of ischemic colon anastomoses and eliminating the negative effects of ischemia.