Successful treatment of massive pulmonary embolism with low-dose tissue plasminogen activator after meniscus surgery

Agus H. Z., Uygur B., Guler A., Demirci G., Kalkan A. K., Yildiz M.

BLOOD COAGULATION & FIBRINOLYSIS, vol.29, no.6, pp.559-561, 2018 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 29 Issue: 6
  • Publication Date: 2018
  • Doi Number: 10.1097/mbc.0000000000000754
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.559-561
  • Istanbul University Affiliated: Yes


Pulmonary embolism is a life-threatening disease which represents with high mortality and morbidity. Systemic fibrinolysis is the first-line recommended therapy in hemodynamically instable patients with massive pulmonary embolism. Systemic fibrinolytic treatment remains controversial for pulmonary embolism after surgery due to high risk of hemorrhage. Herein, we report a 49-year-old man with massive pulmonary embolism after meniscus surgery, successfully treated with low-dose prolonged infusion of tissue type plasminogen activator.