The role of ATP-binding cassette transporter genes in the progression of prostate cancer


KARATAŞ Ö. F. , Guzel E., Duz M. B. , Ittmann M., Ozen M.

PROSTATE, cilt.76, ss.434-444, 2016 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 76 Konu: 5
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1002/pros.23137
  • Dergi Adı: PROSTATE
  • Sayfa Sayıları: ss.434-444

Özet

BACKGROUNDProstate cancer (PCa) is the most commonly diagnosed neoplasm and the second leading cause of cancer-related death among men in developed countries. There is no clear evidence showing the success of current screening tests in reducing mortality of PCa. In this study, we aimed to profile expressions of nine ABC transporters, ABCA5, ABCB1, ABCB6, ABCC1, ABCC2, ABCC3, ABCC5, ABCC10, and ABCF2, in recurrent, non-recurrent PCa and normal prostate tissues.