The role of ATP-binding cassette transporter genes in the progression of prostate cancer

KARATAŞ Ö. F., Guzel E., Duz M. B., Ittmann M., Ozen M.

PROSTATE, vol.76, no.5, pp.434-444, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 76 Issue: 5
  • Publication Date: 2016
  • Doi Number: 10.1002/pros.23137
  • Journal Name: PROSTATE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.434-444
  • Istanbul University Affiliated: Yes

Abstract

BACKGROUNDProstate cancer (PCa) is the most commonly diagnosed neoplasm and the second leading cause of cancer-related death among men in developed countries. There is no clear evidence showing the success of current screening tests in reducing mortality of PCa. In this study, we aimed to profile expressions of nine ABC transporters, ABCA5, ABCB1, ABCB6, ABCC1, ABCC2, ABCC3, ABCC5, ABCC10, and ABCF2, in recurrent, non-recurrent PCa and normal prostate tissues.