Therapeutic vaccination in chronic hepatitis B

---

Atıf İçin Kopyala

Senturk H., Tabak F., Akdogan M., Erdem L., Mert A., Ozaras R., ...Daha Fazla

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, cilt.17, sa.1, ss.72-76, 2002 (SCI-Expanded)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 17 Sayı: 1
• Basım Tarihi: 2002
• Doi Numarası: 10.1046/j.1440-1746.2002.02652.x
• Dergi Adı: JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Sayfa Sayıları: ss.72-76
• İstanbul Üniversitesi Adresli: Evet

Özet

Aims: The aim was to test the efficacy of a pre-S2-containing vaccine (Genhevac-B) in chronic hepatitis B (CHB). Twenty-five naive patients (22 male, three female; median age 35; range: 6-69 years) with CHB were recruited. The inclusion criteria were: hepatitis B e antigen (HBeAg) positive or HBV-DNA detectable with liquid hybridization; alanine aminotransferase (ALT) is at least 1.5-fold the upper normal limit and histological evidence of chronic hepatitis.