Cytokine responses to symbiotic and lactoferrin combination in very low birth weight neonates: a randomized control trial


Pehlevan O. S., Benzer D., Gursoy T., Cetin E., Karatekin G., Ovali F.

ARCHIVOS ARGENTINOS DE PEDIATRIA, cilt.118, sa.1, 2020 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 118 Sayı: 1
  • Basım Tarihi: 2020
  • Doi Numarası: 10.5546/aap.2020.eng.e8
  • Dergi Adı: ARCHIVOS ARGENTINOS DE PEDIATRIA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
  • Anahtar Kelimeler: cytokines, lactoferrin, necrotizing enterocolitis, prebiotics, probiotics, NECROTIZING ENTEROCOLITIS, T-CELLS, IN-VITRO, PROBIOTICS, INFANTS, INTERLEUKIN-10, SYNBIOTICS, PREBIOTICS, PATHOGENESIS
  • İstanbul Üniversitesi Adresli: Evet

Özet

Introduction. Probiotics and prebiotics, which are multifunctional agents, have potential benefits in chronic mucosal inflammation, including the prevention of necrotizing enterocolitis. However, the mechanisms and the results of these immunomodulatory effects are not clear. This study aimed to investigate the cytokine response to the combination of Lactobacillus and Bifidobacterium together with fructo- and galacto-oligosaccharides (symbiotic) and lactoferrin in very low birth weight neonates.