Nailfold capillaroscopy: A sensitive method for evaluating microvascular involvement in children with SARS-CoV-2 infection.

Creative Commons License

Çakmak F., Demirbuga A., Demirkol D., Gümüş S., Torun S., Kayaalp G. K. , ...More

Microvascular research, vol.138, pp.104196, 2021 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 138
  • Publication Date: 2021
  • Doi Number: 10.1016/j.mvr.2021.104196
  • Journal Name: Microvascular research
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database
  • Page Numbers: pp.104196
  • Keywords: COVID-19, Nailfold videocapillaroscopy, Microcirculation, Endotheliitis, CHILDHOOD RHEUMATIC-DISEASES, SYSTEMIC-SCLEROSIS, MICROSCOPY, DAMAGE
  • Istanbul University Affiliated: Yes


Objectives: The hyperinflammatory state and the viral invasion may result in endothelial dysfunction in SARS-CoV-2 infection. Although a method foreseeing microvascular dysfunction has not been defined yet, studies conducted in patients diagnosed with COVID-19 have demonstrated the presence of endotheliitis. With this study, we aimed to investigate the microvascular circulation in patients diagnosed with COVID-19 and multi-system inflammatory syndrome in children (MIS-C) by nailfold videocapillaroscopy (NVC).