The Presence of Donor-Specific Antibodies in Renal Transplantation

Tozkir, H.; Sagiroglu, T.; Kilicarslan-Ayna, T.; Tan, S.; Copuroglu, E.; Sagiroglu, G.; Sari, G.; Gurkan, H.; Sezer, A.

doi:10.1016/j.transproceed.2012.05.052

The Presence of Donor-Specific Antibodies in Renal Transplantation

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Tozkir H., Sagiroglu T., Kilicarslan-Ayna T., Tan S., Copuroglu E., Sagiroglu G., ...More

TRANSPLANTATION PROCEEDINGS, vol.44, no.6, pp.1667-1669, 2012 (SCI-Expanded)

Publication Type: Article / Article
Volume: 44 Issue: 6
Publication Date: 2012
Doi Number: 10.1016/j.transproceed.2012.05.052
Journal Name: TRANSPLANTATION PROCEEDINGS
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.1667-1669
Istanbul University Affiliated: Yes

Abstract

Determining the presence of anti-HLA antibodies before transplantation is an important factor to prevent loss of function among renal transplantations. In addition, recent studies have shown that not only the pretransplantation existence of anti-HLA antibody but also posttransplantation donor-specific antibodies (DSA) and non-donor-specific antibodies are significantly associated with allograft rejection or loss of graft function. This study presented DSA among patients after renal transplantation together with graft function and survival.