Effects of Nasal CPAP Treatment on Insulin Resistance, Lipid Profile, and Plasma Leptin in Sleep Apnea
LUNG, vol.187, no.2, pp.75-81, 2009 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 187 Issue: 2
- Publication Date: 2009
- Doi Number: 10.1007/s00408-008-9131-5
- Journal Name: LUNG
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.75-81
- Istanbul University Affiliated: Yes
Abstract
Background Obstructive sleep apnea has been linked with metabolic syndrome characterized by dyslipidemia, dyscoagulation, hypertension, and diabetes mellitus type 2 and their cardiovascular consequences. This study was designed to determine the effects of 8 weeks of therapy with continuous positive airway pressure (CPAP) on insulin resistance, glucose, and lipid profile, and the relationship between leptin and insulin-resistance parameters in patients with moderate-to-severe obstructive sleep apnea.