Effects of Nasal CPAP Treatment on Insulin Resistance, Lipid Profile, and Plasma Leptin in Sleep Apnea

Cuhadaroglu C., Utkusavas A., ÖZTÜRK L., Salman S., Ece T.

LUNG, cilt.187, sa.2, ss.75-81, 2009 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 187 Sayı: 2
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1007/s00408-008-9131-5
  • Dergi Adı: LUNG
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.75-81
  • İstanbul Üniversitesi Adresli: Evet

Özet

Background Obstructive sleep apnea has been linked with metabolic syndrome characterized by dyslipidemia, dyscoagulation, hypertension, and diabetes mellitus type 2 and their cardiovascular consequences. This study was designed to determine the effects of 8 weeks of therapy with continuous positive airway pressure (CPAP) on insulin resistance, glucose, and lipid profile, and the relationship between leptin and insulin-resistance parameters in patients with moderate-to-severe obstructive sleep apnea.