Joint immobilization increases reactive oxygen species: an experimental study

Erdem M., GÜNEŞ T., ŞEN C., Bostan B., Aslan H., Ozyurt H., ...Daha Fazla

ACTA ORTHOPAEDICA ET TRAUMATOLOGICA TURCICA, cilt.43, sa.5, ss.436-443, 2009 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 43 Sayı: 5
  • Basım Tarihi: 2009
  • Doi Numarası: 10.3944/aott.2009.436
  • Dergi Adı: ACTA ORTHOPAEDICA ET TRAUMATOLOGICA TURCICA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.436-443
  • Anahtar Kelimeler: Antioxidants, cartilage, articular/pathology, immobilization, knee joint, osteoarthritis, oxidative stress, rabbits, reactive oxygen species, tibia/pathology, time factors, ARTICULAR-CARTILAGE, SUPEROXIDE-DISMUTASE, LIPID-PEROXIDATION, KNEE-JOINT, OSTEOARTHRITIS, REMOBILIZATION, DEGRADATION, RADICALS, FLUID
  • İstanbul Üniversitesi Adresli: Evet

Özet

Objectives: It has been shown that reactive oxygen species (ROS) contribute to the onset and progression of osteoarthritis. We investigated cartilage destruction and oxidative stress parameters in the blood and synovial fluid of knee joints of rabbits exposed to varying periods of immobilization.