The increased transglutaminase 2 expression levels during initial tumorigenesis predict increased risk of metastasis and decreased disease-free and cancer-specific survivals in renal cell carcinoma.

Erdem, Selçuk; Yegen, Gülçin; Telci, Dilek; Yildiz, Ibrahim; Tefik, Tzevat; Issever, Halim; Kilicaslan, Isin; Sanli, Mehmet

doi:10.1007/s00345-014-1462-7

The increased transglutaminase 2 expression levels during initial tumorigenesis predict increased risk of metastasis and decreased disease-free and cancer-specific survivals in renal cell carcinoma.

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Erdem S., Yegen G., Telci D., Yildiz I., Tefik T., Issever H., ...More

World journal of urology, vol.33, no.10, pp.1553-60, 2015 (SCI-Expanded)

Publication Type: Article / Article
Volume: 33 Issue: 10
Publication Date: 2015
Doi Number: 10.1007/s00345-014-1462-7
Journal Name: World journal of urology
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.1553-60
Keywords: Renal cell carcinoma, Transglutaminase 2, Tumor marker, Metastasis, TISSUE TRANSGLUTAMINASE, ADHESION
Istanbul University Affiliated: Yes

Abstract

The aim of this study was to investigate the role of transglutaminase 2(TG2) in renal cell carcinoma (RCC) by comparing the immunohistochemistry staining of primary and metastatic tumor tissues.