Effect of Carnosine on Renal Function, Oxidation and Glycation Products in the Kidneys of High-Fat Diet/Streptozotocin-Induced Diabetic Rats


Aydin A. F. , Kucukgergin C. , Bingul I. , Dogan-Ekici I., Dogru-Abbasoglu S. , Uysal M.

EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES, cilt.125, ss.282-289, 2017 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 125 Konu: 5
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1055/s-0043-100117
  • Dergi Adı: EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES
  • Sayfa Sayıları: ss.282-289

Özet

Background High fat diet (HFD) and low dose of streptozotocin (STZ)-treated rats provide an animal model for type 2 Diabetes Mellitus (T2DM). Oxidative stress plays a role in the development of diabetic complications. Carnosine (CAR) has antioxidant and antiglycating properties. We investigated effects of CAR on renal function, oxidation and glycation products in HFD + STZ-rats.