Endobronchial Stenosis due to Wegener Granulomatosis


ERELEL M., Yakar F., Yakar A.

JOURNAL OF BRONCHOLOGY & INTERVENTIONAL PULMONOLOGY, cilt.16, sa.3, ss.221-223, 2009 (ESCI) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 16 Sayı: 3
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1097/lbr.0b013e3181af7aba
  • Dergi Adı: JOURNAL OF BRONCHOLOGY & INTERVENTIONAL PULMONOLOGY
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus
  • Sayfa Sayıları: ss.221-223
  • Anahtar Kelimeler: Wegener granulomatosis, endobronchial stenosis
  • İstanbul Üniversitesi Adresli: Evet

Özet

Wegener granulomatosis (WG) is characterized by a necrotizing granulomatous vasculitis. Computed tomography of the chest is effective in detecting lung involvement with pulmonary nodules with or without cavitations and airspace consolidation. We report a case of endobronchial stenoses in the setting of WG. A 48-year-old man was admitted with complaints of dyspnea, cough, and sputum. A computed tomography scan revealed consolidation and small cavitating nodules, and stenoses were observed during bronchoscopy endobronchial. Narrowing improved after pulse cyclophosphamide and prednisolone therapy. Endobronchial stenoses are rare in the course of WG, and occur even more rarely than subglottic stenosis. Combined treatment with cytotoxic and corticosteroid agents has improved prognosis and long-term survival in patients with WG.