Association of MDR1 Gene Polymorphism in Patients With Temporal Lobe Epilepsy

ÇİNE N., Sargin G., Bebek N., Gurses C., Baykan B., Ozbek U., ...Daha Fazla

JOURNAL OF NEUROLOGICAL SCIENCES-TURKISH, cilt.30, sa.1, ss.4-11, 2013 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 30 Sayı: 1
  • Basım Tarihi: 2013
  • Dergi Adı: JOURNAL OF NEUROLOGICAL SCIENCES-TURKISH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.4-11
  • İstanbul Üniversitesi Adresli: Evet

Özet

Objective: 30-40% of patients with epilepsy have resistance to medical treatment. The major genetic mechanism postulated to underlie this resistance known as Multidrug resistance gene 1 (MDR1), transports the drugs from intracellular to extracellular area.