JOURNAL OF NEUROLOGICAL SCIENCES-TURKISH, cilt.30, sa.1, ss.4-11, 2013 (SCI-Expanded)
Objective: 30-40% of patients with epilepsy have resistance to medical treatment. The major genetic mechanism postulated to underlie this resistance known as Multidrug resistance gene 1 (MDR1), transports the drugs from intracellular to extracellular area.