Association of MDR1 Gene Polymorphism in Patients With Temporal Lobe Epilepsy

ÇİNE, NACİ; Sargin, Gulcan; Bebek, NERSES; Gurses, Candan; Baykan, Betül; Ozbek, Ugur; Gokyigit, Aysen

Association of MDR1 Gene Polymorphism in Patients With Temporal Lobe Epilepsy

ÇİNE N., Sargin G., Bebek N., Gurses C., Baykan B., Ozbek U., ...Daha Fazla

JOURNAL OF NEUROLOGICAL SCIENCES-TURKISH, cilt.30, sa.1, ss.4-11, 2013 (SCI-Expanded, Scopus, TRDizin)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 30 Sayı: 1
Basım Tarihi: 2013
Dergi Adı: JOURNAL OF NEUROLOGICAL SCIENCES-TURKISH
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
Sayfa Sayıları: ss.4-11
İstanbul Üniversitesi Adresli: Evet

Özet

Objective: 30-40% of patients with epilepsy have resistance to medical treatment. The major genetic mechanism postulated to underlie this resistance known as Multidrug resistance gene 1 (MDR1), transports the drugs from intracellular to extracellular area.