ACTA NEUROLOGICA SCANDINAVICA, cilt.114, sa.4, ss.239-243, 2006 (SCI-Expanded)
Objective – To identify features related to the development of
hallucinations in Parkinson’s disease (PD). Materials and methods –
Seventy PD patients with hallucinations (group 1) and 60 PD patients
without hallucinations (group 2) were evaluated for disease severity,
presence of motor complications, rapid eye movement (REM) behavior
disorder (RBD), and antiparkinsonian drug profile. The ages at the
emergence of hallucinations and duration of disease in group 1 were
matched with the ages at the last visit of those in group 2.
Results – Disease severity and presence of motor complications were similar in both
groups. RBD was more frequently encountered among hallucinators
thanamongnon-hallucinators. The mean duration and daily
doses of levodopa and other dopaminergic drugs did not differ in both
groups; however, the usage of anticholinergics and amantadine were
significantly more frequent in group 2, unexpectedly.
Conclusions – The presence of RBD was significantly more common in hallucinators;
however,severityofPD,duration and
daily doses of dopaminergic drugs
were not associated with the emergence of hallucinations