Production of the novel fibrous structure of poly(epsilon-caprolactone)/tri-calcium phosphate/hexagonal boron nitride composites for bone tissue engineering
JOURNAL OF THE AUSTRALIAN CERAMIC SOCIETY, vol.54, no.2, pp.251-260, 2018 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 54 Issue: 2
- Publication Date: 2018
- Doi Number: 10.1007/s41779-017-0149-0
- Journal Name: JOURNAL OF THE AUSTRALIAN CERAMIC SOCIETY
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.251-260
- Keywords: Biopolymers, Biofibers, Biomaterials, Poly(epsilon-caprolactone), Composites, POLYCAPROLACTONE, SCAFFOLDS, FABRICATION
- Istanbul University Affiliated: Yes
Abstract
Nanofibrous composites of the poly(epsilon-caprolactone) (PCL), tricalcium phosphate (TCP), and hexagonal boron nitride (h-BN) with different compositions were manufactured by using an economical and non-complicated method called electrospinning. Produced fibrous structures showed no bead formation and had a clean surface. Characterization of the composites showed that particles were successfully mixed with polymer phase. High cell activity of SaOS-2 cells on the composites was observed with SEM images. In addition, fibrous scaffolds are biocompatible with human bone tissue and are highly degradable.