Effects of diclofenac and tenoxicam on distraction osteogenesis

ŞEN C., Erdem M., Gunes T., Koseoglu D., Filiz N. O.

ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY, vol.127, no.3, pp.153-159, 2007 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 127 Issue: 3
  • Publication Date: 2007
  • Doi Number: 10.1007/s00402-006-0274-7
  • Journal Name: ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.153-159
  • Keywords: distraction osteogenesis, diclofenac, tenoxicam, ilizarov, NONSTEROIDAL ANTIINFLAMMATORY DRUGS, BONE, OSTEOTOMIES, INDOMETHACIN, INHIBITION, RABBITS, RAT
  • Istanbul University Affiliated: No

Abstract

Introduction In the management of bone defects, pseudoarthrosis, deformities, chronic osteomyelitis and in extremity lengthening procedures, the technique of distraction osteogenesis (DO) has been frequently used. In this experimental animal study, the effects of two non-steroidal anti-inflammatory drugs, i.e., diclofenac and tenoxicam, on the outcomes of distraction osteogenesis are investigated.