DLEC1 is not silenced solely by promoter methylation in head and neck squamous cell carcinoma

Seven D., Yavuz E. , Kilic E., Baltaci E., Karaman E. , Ulutin T., ...Daha Fazla

GENE, cilt.563, ss.83-86, 2015 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 563 Konu: 1
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1016/j.gene.2015.03.004
  • Dergi Adı: GENE
  • Sayfa Sayıları: ss.83-86


Different types of genetic and epigenetic changes are associated with HNSCC. The molecular mechanisms of HNSCC carcinogenesis are still undergoing intensive investigation. The Deleted in lung and esophageal cancer 1 (DLEC1) gene is frequently silenced by methylation in various kinds of cancer. However, there is no data in the literature investigating the DLEC1 gene in the HNSCC.