Spread of OXA-48-Encoding Plasmid in Turkey and Beyond


Carrer A., Poirel L., Yilmaz M., Akan O. A. , Feriha C., Cuzon G., ...More

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, vol.54, no.3, pp.1369-1373, 2010 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 54 Issue: 3
  • Publication Date: 2010
  • Doi Number: 10.1128/aac.01312-09
  • Title of Journal : ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
  • Page Numbers: pp.1369-1373

Abstract

Eighteen carbapenem-resistant, OXA-48-positive enterobacterial isolates recovered from Turkey, Lebanon, Egypt, France, and Belgium were analyzed. In most isolates, similar 70-kb plasmids carrying the carbapenemase gene bla(OXA-48) were identified. That gene was located within either transposon Tn1999 or transposon Tn1999.2, which was always inserted within the same gene. This work highlights the current plasmid-mediated dissemination of the OXA-48 carbapenemase worldwide.