Impact of JAK2V617F Mutational Status on Phenotypic Features in Essential Thrombocythemia and Primary Myelofibrosis

Yonal I. , Daglar-Aday A. , Akadam-Teker B., Yilmaz C., Nalcaci M. , Yavuz A., ...Daha Fazla

TURKISH JOURNAL OF HEMATOLOGY, cilt.33, ss.94-101, 2016 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 33 Konu: 2
  • Basım Tarihi: 2016
  • Doi Numarası: 10.4274/tjh.2014.0136
  • Dergi Adı: TURKISH JOURNAL OF HEMATOLOGY
  • Sayfa Sayıları: ss.94-101

Özet

Objective: The JAK2V617F mutation is present in the majority of patients with essential thrombocythemia (ET) and primary myelofibrosis (PMF). The impact of this mutation on disease phenotype in ET and PMF is still a matter of discussion. This study aims to determine whether there are differences in clinical presentation and disease outcome between ET and PMF patients with and without the JAK2V617F mutation.