Surface enhanced vibrational spectroscopic evidence for an alternative DNA-independent redox activation of endonuclease III

Moe E., SEZER M., Hildebrandt P., Todorovic S.

CHEMICAL COMMUNICATIONS, vol.51, no.15, pp.3255-3257, 2015 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 51 Issue: 15
  • Publication Date: 2015
  • Doi Number: 10.1039/c4cc09498k
  • Journal Name: CHEMICAL COMMUNICATIONS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.3255-3257
  • Istanbul University Affiliated: No

Abstract

Surface enhanced vibrational spectro-electrochemistry of endonuclease III provides direct evidence that the [4Fe-4S] cluster is responsible for the enzyme redox activity, and that this process is not exclusively DNA-mediated, as currently proposed. We report the first surface enhanced resonance Raman spectrum of a [4Fe-4S](2+) cluster containing enzyme.