The inhibitory effect of suramin on telomerase activity and spheroid growth of C6 glioma cells
MEDICAL SCIENCE MONITOR, vol.14, no.8, 2008 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 14 Issue: 8
- Publication Date: 2008
- Journal Name: MEDICAL SCIENCE MONITOR
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Open Archive Collection: AVESIS Open Access Collection
- Istanbul University Affiliated: Yes
Abstract
Background: The significant roles of telomerase in carcinogenesis and drug resistance have attracted growing attention as potential therapies. The aim of the study was to investigate the effect of suramin on the telomerase activity of C6 glioma cells and on the growth of C6 glioma spheroids.