Evaluation of insulin-like growth factor (IGF)-I and IGF binding protein-3 generation test in short stature


Darendeliler F. F. , OCAL C., BAS F.

JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM, cilt.18, ss.443-452, 2005 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 18 Konu: 5
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1515/jpem.2005.18.5.443
  • Dergi Adı: JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
  • Sayfa Sayıları: ss.443-452

Özet

Background: Differentiation between growth hormone deficiency (GHD) and idiopathic short stature (ISS) based on GH tests and basal IGF-I and IGFBP-3 levels may be difficult. The aim of this study was to evaluate the role of pharmacological GH tests, IGF-I and IGFBP-3 generation test and height velocity off-treatment in the evaluation of GHD and ISS.