Investigation of Gene Expressions of Myeloma Cells in the Bone Marrow of Multiple Myeloma Patients by Transcriptome Analysis

Sariman M., Abaci N., Ekmekci S., Cakiris A., Pacal F., Ustek D., ...Daha Fazla

Balkan medical journal, cilt.36, sa.1, ss.23-31, 2019 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 36 Sayı: 1
  • Basım Tarihi: 2019
  • Doi Numarası: 10.4274/balkanmedj.2018.0356
  • Dergi Adı: Balkan medical journal
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.23-31
  • Anahtar Kelimeler: Flow cytometry, gene expresion, multiple myeloma, plasma cell dyscrasias, transcriptome analyses, UBIQUITIN-PROTEASOME PATHWAY, PROGNOSTIC-SIGNIFICANCE, PLASMA-CELLS, PATHOGENESIS, ANTIBODY, DISEASE, TARGET
  • İstanbul Üniversitesi Adresli: Evet

Özet

Background: Multiple myeloma is a plasma cell dyscrasia characterized by transformation of B cells into malignant cells. Although there are data regarding the molecular pathology of multiple myeloma, the molecular mechanisms of the disease have not been fully elucidated.