PHOTOINSTABILITY AND DEGRADATION KINETICS OF MEDAZEPAM
PHARMAZIE, cilt.50, sa.2, ss.119-121, 1995 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 50 Sayı: 2
- Basım Tarihi: 1995
- Dergi Adı: PHARMAZIE
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.119-121
- İstanbul Üniversitesi Adresli: Evet
Özet
As a consequence of irradiation of medazepam in an aprotic solution, 7-chloro-2,3-dihydro-1,5-epoxy-1-methyl-5-phenyl-1 H-1,4-benzodiazepine or 7-chloro-2,3-dihydro-1-methyl-5-phenyl-1 H-1,4-benzodiazepine 4-oxide was formed. It was observed that the degradation rate was rather high and a t(90) value of 3.16 h calculated.