Hyperbaric oxygen treatment for refractory haemorrhagic cystitis occurring after chemotherapy and haematopoietic stem cell transplantation: retrospective analysis of 25 patients

Ozturk H., Mirasoglu B., Aktas Ş.

DIVING AND HYPERBARIC MEDICINE, vol.52, no.1, pp.27-34, 2022 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 52 Issue: 1
  • Publication Date: 2022
  • Doi Number: 10.28920/dhm52.1.27-34
  • Journal Name: DIVING AND HYPERBARIC MEDICINE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
  • Page Numbers: pp.27-34
  • Keywords: Cyclophosphamide, Hematopoietic stem cell transplantation, Hemorrhagic cystitis, Hyperbaric research, CONTINUOUS BLADDER IRRIGATION, BK-VIRUS, CLINICAL EFFECTIVENESS, THERAPY, PREVENTION, MANAGEMENT, CHILDREN, CHAMBER, MESNA
  • Istanbul University Affiliated: Yes

Abstract

Introduction: Intractable haemorrhagic cystitis (HC) is a serious complication of chemotherapy (CT) and haematopoietic stem cell transplantation (HSCT). Hyperbaric oxygen treatment (HBOT) is a promising treatment option based on the similarities in injury pattern and observed histological changes with radiation induced HC, which is an approved indication. We present our experience with HBOT in HC occurring after CT and HSCT.