Acute cerebellitis, transverse myelitis and polyradiculoneuritis related to post-COVID-19 infection


Boru U. T., Boluk C., Toksoy C. K., Demirbas H.

JOURNAL OF SPINAL CORD MEDICINE, cilt.45, sa.5, ss.765-768, 2022 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 45 Sayı: 5
  • Basım Tarihi: 2022
  • Doi Numarası: 10.1080/10790268.2021.1969502
  • Dergi Adı: JOURNAL OF SPINAL CORD MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CINAHL, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.765-768
  • Anahtar Kelimeler: COVID-19, Cerebellitis, Transverse myelitis, Guillain-Barre syndrome
  • İstanbul Üniversitesi Adresli: Hayır

Özet

Context Guillain-Barre syndrome (GBS), acute cerebellitis and transverse myelitis are rare complications of COVID-19 infection separately. The combination of these three, however, has not yet been reported. Findings We present an atypical case (42-year-old man) that developed acute ascending flaccid paraparesis, ataxia and urinary retention two weeks after COVID-19 infection. Neurological examination revealed distal and proximal weakness (4/5) on lower extremities, decreased tendon reflexes, sixth cranial nerve palsy and dysmetria without sensory disturbance. His cranial MRI showed cerebellitis whereas the spinal MRI showed transverse myelitis at the T11/12 level. Albuminocytologic dissociation was present in the cerebrospinal fluid. The nerve conduction study was concordant with early findings of GBS. He recovered well after corticosteroid treatment without needing any immunotherapy. On day seven of hospitalization, the modified Rankin Scale score was 0. Conclusion COVID-19 infection may present with a combination of neurological manifestations such as cerebellitis, transverse myelitis and GBS. This patient presented significant functional recovery after treatment with corticosteroid without immunotherapy.