Bioinformatic challenge on prostate cancer and urinary microbiome


Davasaz Tabrizi E., Mushteba S., Sajer Naser O., Arıcan E.

REVISTA LATINOAMERICANA DE HIPERTENSION, cilt.18, sa.6, ss.266-273, 2023 (ESCI)

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 18 Sayı: 6
  • Basım Tarihi: 2023
  • Doi Numarası: 10.5281/zenodo.10029975
  • Dergi Adı: REVISTA LATINOAMERICANA DE HIPERTENSION
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus
  • Sayfa Sayıları: ss.266-273
  • İstanbul Üniversitesi Adresli: Evet

Özet

The Bioinformatics Resource Center (BRC) program was developed by the National Institute of Allergy and Infectious Diseases (NIAID) to assist researchers in analyzing the increasing amount of genomic sequences and other omics-related data. In this work, whole-genome sequences of prostate cancer and genitourinary diseases (WGS) were examined for genes utilizing the BV-BRC Bioinformatics Resource Center. using the Usegalaxy program to combine the plasma and gut microbiome sequences from prostate cancer patients. Following that, chromosomes, plasmids, and unclassified sequences were subjected to ARG analysis. As a result of comprehensive genomic analysis of all samples, the S2 sequences were of good quality compared to the other sequences. As for virulence factors, intracellular survival is one of the important virulence factors, a common gene of Salmonella, which was represented in the prostate cancer samples but not in the urine microbiome samples.