Anti-beta 2-glycoprotein I, anti-prothrombin and anticardiolipin antibodies in a longitudinal study of patients with systemic lupus erythematosus and the antiphospholipid syndrome
BRITISH JOURNAL OF RHEUMATOLOGY, cilt.37, sa.10, ss.1089-1094, 1998 (SCI-Expanded)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 37 Sayı: 10
- Basım Tarihi: 1998
- Dergi Adı: BRITISH JOURNAL OF RHEUMATOLOGY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED)
- Sayfa Sayıları: ss.1089-1094
- Anahtar Kelimeler: systemic lupus erythematosus, antiphospholipid syndrome, anti-beta 2 glycoprotein-I, anti-prothrombin, CLINICAL MANIFESTATIONS, GLYCOPROTEIN-I, BETA-2-GLYCOPROTEIN-I, ELISA, BETA(2)-GLYCOPROTEIN-I, AUTOANTIBODIES, SPECIFICITY, ASSAY
- İstanbul Üniversitesi Adresli: Evet
Özet
Objective. To determine anti-beta 2 glycoprotein-I (anti-beta 2GPI) and anti-prothrombin (anti-ProT) antibody levels, and the IgG subclass distribution of anti-beta 2GPI antibodies, in serial samples from patients with systemic lupus erythematosus (SLE) and antiphospholipid syndrome (APS) having initial or recurrent thrombotic/neurological (T/N) events during the study period. To investigate the correlations between these antibodies and beta 2GPI antigen, anticardiolipin antibody (aCL), anti-double-stranded (ds) DNA, C3 levels and disease activity.