Prognostic Factors and Tumor Infiltrating Lymphocytes in Triple Negative Breast Cancer


Dulgar O., İLVAN Ş., TURNA Z. H.

EUROPEAN JOURNAL OF BREAST HEALTH, vol.16, no.4, pp.276-281, 2020 (ESCI, TRDizin)

  • Publication Type: Article / Article
  • Volume: 16 Issue: 4
  • Publication Date: 2020
  • Doi Number: 10.5152/ejbh.2020.5305
  • Journal Name: EUROPEAN JOURNAL OF BREAST HEALTH
  • Journal Indexes: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Page Numbers: pp.276-281
  • Istanbul University Affiliated: No

Abstract

Objective: Triple-negative-breast-cancer (TNBC) is a very heterogenous disease some of which are very aggressive and have poor prognosis. No targeted therapy is available. Immune response and tumor-infiltrating lymphocytes (TIL) can be related to longer disease-free survival (DFS) and overall survival (OS) in TNBC. Family history of cancer can be related poor prognosis, irrespective of genetic mutation.