Polymorphisms of DNA repair genes XRCC1 and XPD and risk of primary open angle glaucoma (POAG)

Guven M. , Unal M., Batar B. , Eroglu E., Devaroglu K., Tamcelik N. , ...Daha Fazla

MOLECULAR VISION, cilt.13, ss.12-17, 2007 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 13
  • Basım Tarihi: 2007
  • Sayfa Sayıları: ss.12-17


Purpose: Oxidative DNA damage has been shown to have some role in the development of primary open angle glaucoma (POAG). In this study, we aimed to determine the frequency of polymorphisms in two DNA repair enzyme genes, Xeroderma pigmentosum complementation group D (XPD) codon 751 and X-ray cross-complementing group 1 (XRCC1) codon 399, in a sample of Turkish patients with POAG, and to evaluate their association with POAG development.