Temperature dependent FTIR spectroscopic study of the interaction of alpha-tocopherol and alpha-tocopheryl acetate with phospholipid bilayers

Akyuz S., Davies J.

JOURNAL OF MOLECULAR STRUCTURE, cilt.415, ss.65-70, 1997 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 415
  • Basım Tarihi: 1997
  • Doi Numarası: 10.1016/s0022-2860(97)00086-0
  • Dergi Adı: JOURNAL OF MOLECULAR STRUCTURE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.65-70
  • İstanbul Üniversitesi Adresli: Hayır

Özet

FTIR spectroscopy has been employed in order to investigate alpha-tocopherol (alpha-T) and alpha-tocopheryl acetate (alpha-TA) induced effects on the molecular organization of dimyristoyl-L-alpha-phosphatidylcholine (DMPC) bilayers, at various temperatures and concentrations. It was concluded that alpha-T interacts much more strongly than alpha-TA, indicating that alpha-T has a more polar location in the membrane than alpha-TA. The observed changes in the carbonyl and phosphate group vibrational modes of DMPC on addition of alpha-T or alpha-TA are discussed. (C) 1997 Elsevier Science B.V.