Triple Negative Breast Cancer
ASIAN PACIFIC JOURNAL OF CANCER PREVENTION, cilt.15, sa.6, ss.2427-2431, 2014 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Derleme
- Cilt numarası: 15 Sayı: 6
- Basım Tarihi: 2014
- Doi Numarası: 10.7314/apjcp.2014.15.6.2427
- Dergi Adı: ASIAN PACIFIC JOURNAL OF CANCER PREVENTION
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.2427-2431
- Anahtar Kelimeler: Triple negative breast cancer, poor prognosis, targeted therapy, ENDOTHELIAL GROWTH-FACTOR, FACTOR RECEPTOR, MOLECULAR SUBTYPES, RISK-FACTORS, STEM-CELLS, PROGNOSTIC VALUE, BASAL, CHEMOTHERAPY, CARCINOMA, SURVIVAL
- İstanbul Üniversitesi Adresli: Evet
Özet
Triple-negative breast cancers (TNBC), characterized by absence of the estrogen receptor (ER) and progesterone receptor (PR) and lack of overexpression of human epidermal growth factor receptor 2 (HER2), have a poor prognosis. To overcome therapy limitations of TNBC, various new approaches are needed. This mini-review focuses on discovery of new targets and drugs which might offer new hope for TNBC patients.