Triple Negative Breast Cancer

Cetin I., Topcul M.

ASIAN PACIFIC JOURNAL OF CANCER PREVENTION, cilt.15, sa.6, ss.2427-2431, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 15 Sayı: 6
  • Basım Tarihi: 2014
  • Doi Numarası: 10.7314/apjcp.2014.15.6.2427
  • Dergi Adı: ASIAN PACIFIC JOURNAL OF CANCER PREVENTION
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.2427-2431
  • Anahtar Kelimeler: Triple negative breast cancer, poor prognosis, targeted therapy, ENDOTHELIAL GROWTH-FACTOR, FACTOR RECEPTOR, MOLECULAR SUBTYPES, RISK-FACTORS, STEM-CELLS, PROGNOSTIC VALUE, BASAL, CHEMOTHERAPY, CARCINOMA, SURVIVAL
  • İstanbul Üniversitesi Adresli: Evet

Özet

Triple-negative breast cancers (TNBC), characterized by absence of the estrogen receptor (ER) and progesterone receptor (PR) and lack of overexpression of human epidermal growth factor receptor 2 (HER2), have a poor prognosis. To overcome therapy limitations of TNBC, various new approaches are needed. This mini-review focuses on discovery of new targets and drugs which might offer new hope for TNBC patients.