Interleukin-12 and Protamine Inhibit Angiogenesis and Growth of C6 Rat Glioma: Synergistic Effects and Role of Th2 Cells

TURNA A., KIRAN B., Ozar E., TURNA Z. H., Mercan C. A., Buyukpinarbasili N., ...Daha Fazla

TURKISH JOURNAL OF IMMUNOLOGY, cilt.1, sa.3, ss.68-73, 2013 (ESCI) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 1 Sayı: 3
  • Basım Tarihi: 2013
  • Doi Numarası: 10.5606/tji.2013.268
  • Dergi Adı: TURKISH JOURNAL OF IMMUNOLOGY
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus
  • Sayfa Sayıları: ss.68-73
  • Anahtar Kelimeler: Angiogenesis, C6, glioma, interleukin-12, lymphocyte, protamine, Th1 cell, Th2 cell
  • İstanbul Üniversitesi Adresli: Evet

Özet

Objectives: This study aims to investigate the anti-tumoral, anti-angiogenic and immunologic effects of interleukin-12 (IL-12) in combination with protamine in intracranially inoculated rat C6 glioma model.