Manganese superoxide dismutase gene polymorphism, MnSOD plasma levels and risk of epithelial ovarian cancer

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Dalan A. B., Ergen A., Yilmaz H., KARATEKE A., Isbir T.

JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH, cilt.34, sa.5, ss.878-884, 2008 (SCI-Expanded, Scopus)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 34 Sayı: 5
• Basım Tarihi: 2008
• Doi Numarası: 10.1111/j.1447-0756.2008.00851.x
• Dergi Adı: JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Sayfa Sayıları: ss.878-884
• Anahtar Kelimeler: ELISA, epithelial ovarian cancer, manganese superoxide dismutase, RFLP, MITOCHONDRIAL TARGETING SEQUENCE, BREAST-CANCER, OXIDATIVE STRESS, DNA-DAMAGE, UNITED-STATES, EXPRESSION, CELLS, ANTIOXIDANTS, ASSOCIATION, DIMORPHISM
• İstanbul Üniversitesi Adresli: Evet

Özet

Aim: We aimed to confirm any relation between the manganese-containing superoxide dismutase (MnSOD) polymorphism and risk of ovarian carcinoma as well as to demonstrate any relation between the MnSOD mitochondrial signal sequence polymorphism and plasma MnSOD enzyme levels in women with ovarian carcinoma and healthy subjects.